Current Level of Fish Consumption Is Associated with Mortality in Chinese but not U.S. Adults: New Findings from Two Nationwide Cohort Studies with 14 and 9.8 Years of Follow-Up
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SCOPE: Whether dietary fish consumption is linked to mortality remains unclear. We aim to investigate the association of fish consumption with mortality in Chinese and US nationwide populations.
METHODS AND RESULTS: We utilized data from China Health and Nutrition Survey (CHNS, n = 14,117) and National Health and Nutrition Examination Survey (NHANES, n = 33,221) including NHANES III conducted in 1988-1994 and continuous NHANES 1999-2010. Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). During a median follow-up of 14 and 9.8 years for CHNS and NHANES, 1007 and 5209 deaths were documented, respectively. Among Chinese adults, increased fish intake was significantly associated with decreased total mortality. The multivariable-adjusted HRs (95% CIs) across increasing categories of fish intake were 0.45 (0.36-0.56), 0.72 (0.60-0.86) and 0.70 (0.59-0.85) (P trend < 0.0001). However, fish intake was not associated with total mortality among US adults (P trend = 0.21). We only detected a borderline inverse association between fish intake and stroke mortality (P trend = 0.05), whereas a positive association with diabetes mortality in the third category of fish intake in NHANES.
CONCLUSION: In these two nationwide cohort studies, fish consumption is associated with a reduced risk of total mortality for Chinese but not US populations. This article is protected by copyright. All rights reserved.
JOUR
Zhuang, Pan
Wang, Wenqiao
Wang, Jun
Zhang, Yu
Jiao, Jingjing
2018
Molecular Nutrition & Food Research
62
8
e1700898
2622