Prospective Validation of a Perinatal Bacterial Vaginosis Screening Risk Score

Reference Type:
Journal Article

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Author(s):
Pastore, Lisa M.
King, Tonya S.
Dawson, Ida J.
Hollifield, Alisa
Thorp, John M., Jr.

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Year Published:
2004

Date Published:

Journal Name:
Journal of Perinatology

Volume Number:
24

Issue Number:
12

Start Page Number:
735-42

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Reference ID:
1415

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Abstract:

OBJECTIVE: Prospectively validate an antenatal bacterial vaginosis (BV) risk score at two public health department obstetrics clinics.

STUDY DESIGN: Women (n=409) entering prenatal care received a BV risk score (range 0 to 16) at their first visit and at 24 to 28 weeks' gestation. BV was measured with Gram-stained vaginal smears. Normal discharge was used as a surrogate for being asymptomatic.

RESULTS: Approximately half of the women scored > or =3 at each assessment. In total 29% had true BV at the first assessment (13% at the second assessment). The BV risk score (> or =3) had 91% sensitivity and 63% specificity, and the BV risk score (> or =5) had 88% sensitivity and 76% specificity. Among true cases, 42% were asymptomatic, of which 77% had risk scores > or =3. All symptomatic BV cases had risk scores > or =3.

CONCLUSION: In practice, the risk score identified both asymptomatic and symptomatic cases. Asymptomatic women are of particular interest because they are not screened for BV under current practice guidelines.

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Citation:

Pastore, Lisa M.; King, Tonya S.; Dawson, Ida J.; Hollifield, Alisa; & Thorp, John M., Jr. (2004). Prospective Validation of a Perinatal Bacterial Vaginosis Screening Risk Score. Journal of Perinatology, 24(12), 735-42.