Measurement of Testosterone in Infant Fecal Samples

Filed under: Biological and Social Interactions

Thompson, Amanda L.; Whitten, Patricia L.; & Lampl, Michelle. (2011). Measurement of Testosterone in Infant Fecal Samples. American Journal of Human Biology, 23(6), 820-2.

Reference Type:
Journal Article

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Series Title:

Author(s):
Thompson, Amanda L.
Whitten, Patricia L.
Lampl, Michelle

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Series Author(s):

Year Published:
2011

Date Published:

Journal Name:
American Journal of Human Biology

Volume Number:
23

Issue Number:
6

Start Page Number:
820-2

End Page Number:

Edition:
20110719

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ISSN/ISBN:

DOI:
10.1002/ajhb.21205

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NIHMSID:

Reference ID:
5041

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Abstract:

OBJECTIVES: This study reports the validation of a noninvasive method for repeated assessment of testosterone from infant fecal samples.
METHODS: Fecal samples were collected from cotton diaper liners, subjected to methanol extraction, and assayed using a modified commercial testosterone RIA kit.
RESULTS: Method validity was supported by a recovery near 100%, a sensitivity of 1.23 pg/ml, and inter- and intra-assay coefficients of variations less than 10 and 15%, respectively. Testosterone was detected in all samples from male and female infants aged 2 weeks to 15 months.
CONCLUSIONS: Fecal assessment is supported as a novel, non-invasive tool for studying testosterone during early human development.

Keyword(s):
Biological and Social Interactions

URL:

http://dx.doi.org/10.1002/ajhb.21205

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Citation:

Thompson, Amanda L.; Whitten, Patricia L.; & Lampl, Michelle. (2011). Measurement of Testosterone in Infant Fecal Samples. American Journal of Human Biology, 23(6), 820-2.