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Prevalence of Human African Trypanosomiasis in the Democratic Republic of the Congo

Mumba, Dieudonne; Bohorquez, Elaine; Messina, Jane P.; Kande, Victor; Taylor, Steven M.; Tshefu, Antoinette K.; Muwonga, Jeremie; Kashamuka, Melchior M.; Emch, Michael E.; Tidwell, Richard; Büscher, Philippe; & Meshnick, Steven R. (2011). Prevalence of Human African Trypanosomiasis in the Democratic Republic of the Congo. PLoS Neglected Tropical Diseases, 5(8), e1246. PMCID: PMC3149009

Journal Article



Mumba, Dieudonne
Bohorquez, Elaine
Messina, Jane P.
Kande, Victor
Taylor, Steven M.
Tshefu, Antoinette K.
Muwonga, Jeremie
Kashamuka, Melchior M.
Emch, Michael E.
Tidwell, Richard
Büscher, Philippe
Meshnick, Steven R.



2011


PLoS Neglected Tropical Diseases

5

8

e1246


20110802





10.1371/journal.pntd.0001246

PMC3149009


5072


Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were positive by ELISA. Three of these were also positive by trypanolysis and/or PCR. From these data, we estimate that there were 18,592 people with HAT (95% confidence interval, 4,883-32,302) in the DRC in 2007, slightly more than twice as many as were reported.


Place, Space, and Health


Octet Stream icon 5072.ris — Octet Stream, 1 kB (1,310 bytes)

Mumba, Dieudonne; Bohorquez, Elaine; Messina, Jane P.; Kande, Victor; Taylor, Steven M.; Tshefu, Antoinette K.; Muwonga, Jeremie; Kashamuka, Melchior M.; Emch, Michael E.; Tidwell, Richard; Büscher, Philippe; & Meshnick, Steven R. (2011). Prevalence of Human African Trypanosomiasis in the Democratic Republic of the Congo. PLoS Neglected Tropical Diseases, 5(8), e1246. PMCID: PMC3149009