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Relating multiple dimensions of stress to CVD risk in Filipino adults

Cardiovascular disease (CVD) and other non-communicable diseases (NCDs) are rapidly becoming leading causes of morbidity and mortality in developing and transitional countries worldwide. Research is needed to identify the factors driving this dramatic change. This project is linked to a parent grant funded by NHLBI, titled "Obesity Development and CVD Risk Factor Clustering in Filipino Women & Offspring" (HL085144). The parent grant focuses on determinants of weight trajectories over a 20 year period, and on how diet, physical activity and weight gain relate to blood pressure and biomarkers of CVD risk. This project extends the parent grant's research to examine the role of a wide range of psychosocial, environmental and behavioral factors that represent multiple dimensions of stress. Both projects use data from the Cebu Longitudinal Health and Nutrition Survey (CLHNS), an ongoing community based cohort study of Filipino mothers and their offspring born in 1983-84. Through this new research, we will strengthen the ongoing research collaboration between the Office of Population Studies Foundation (OPS) at the University of San Carlos in Cebu, Philippines and the University of North Carolina at Chapel and to develop a stronger chronic disease research focus and data analysis capacity at OPS.

Principal Investigator: Linda S. Adair

CPC Fellow Investigator:

Other Investigators: Catherine Zimmer

Funding Source: NIH FIC

Grant Number: 1R03TW008133

Funding Period: 8/1/2008 - 4/30/2012

Related CPC Signature Themes:

Affiliated Research Project: