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Social Relationships, Inflammation, and Cancer Survival

Citation

Boen, Courtney E.; Barrow, David A.; Bensen, Jeannette T.; Farnan, Laura; Gerstel, Adrian A.; Hendrix, Laura H.; & Yang, Yang Claire (2018). Social Relationships, Inflammation, and Cancer Survival. Cancer Epidemiology, Biomarkers & Prevention, 27(5), 541-549. PMCID: PMC5932225

Abstract

Background: Social stressors, such as social relationship deficits, have been increasingly linked to chronic disease outcomes, including cancer. However, critical gaps exist in our understanding of the nature and strength of such links, as well as the underlying biological mechanisms relating social relationships to cancer progression and survival. Methods: Utilizing novel questionnaire and biomarker data from the UNC Health Registry/Cancer Survivorship Cohort, this study examines the associations between diverse measures of social support and mortality risk among individuals with cancer (N = 1,004). We further assess the role of multiple serum markers of inflammation, including high-sensitivity C-reactive protein (CRP), IL6, TNF

URL

http://dx.doi.org/10.1158/1055-9965.EPI-17-0836

Reference Type

Journal Article

Year Published

2018

Journal Title

Cancer Epidemiology, Biomarkers & Prevention

Author(s)

Boen, Courtney E.
Barrow, David A.
Bensen, Jeannette T.
Farnan, Laura
Gerstel, Adrian A.
Hendrix, Laura H.
Yang, Yang Claire

PMCID

PMC5932225