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Social Relationships, Inflammation, and Cancer Survival


Boen, Courtney E.; Barrow, David A.; Bensen, Jeannette T.; Farnan, Laura; Gerstel, Adrian A.; Hendrix, Laura H.; & Yang, Yang Claire (2018). Social Relationships, Inflammation, and Cancer Survival. Cancer Epidemiology, Biomarkers & Prevention, 27(5), 541-549. PMCID: PMC5932225


Background: Social stressors, such as social relationship deficits, have been increasingly linked to chronic disease outcomes, including cancer. However, critical gaps exist in our understanding of the nature and strength of such links, as well as the underlying biological mechanisms relating social relationships to cancer progression and survival. Methods: Utilizing novel questionnaire and biomarker data from the UNC Health Registry/Cancer Survivorship Cohort, this study examines the associations between diverse measures of social support and mortality risk among individuals with cancer (N = 1,004). We further assess the role of multiple serum markers of inflammation, including high-sensitivity C-reactive protein (CRP), IL6, TNF


Reference Type

Journal Article

Year Published


Journal Title

Cancer Epidemiology, Biomarkers & Prevention


Boen, Courtney E.
Barrow, David A.
Bensen, Jeannette T.
Farnan, Laura
Gerstel, Adrian A.
Hendrix, Laura H.
Yang, Yang Claire