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Association of Maternal Depression and Home Adversities with Infant Hypothalamic-Pituitary-Adrenal (HPA) Axis Biomarkers in Rural Pakistan

Citation

Hagaman, Ashley K.; Baranov, Victoria; Chung, Esther O.; LeMasters, Katherine; Andrabi, Nafeesa; Bates, Lisa M.; Rahman, Atif; Sikander, Siham; Turner, Elizabeth L.; & Maselko, Joanna (2020). Association of Maternal Depression and Home Adversities with Infant Hypothalamic-Pituitary-Adrenal (HPA) Axis Biomarkers in Rural Pakistan. Journal of Affective Disorders, 276, 592-9.

Abstract

BACKGROUND: Each year, almost 35% of children are exposed to maternal depression and more grow up in persistent poverty, increasing the risk for stress-related disease and other socio-developmental deficits later in life. These impacts are likely related to chronic stress via the hypothalamic-pituitary-adrenal (HPA) axis. However, there is little evidence relating early windows of child HPA axis activity to multiple exposures.

URL

http://dx.doi.org/10.1016/j.jad.2020.07.053

Reference Type

Journal Article

Journal Title

Journal of Affective Disorders

Author(s)

Hagaman, Ashley K.
Baranov, Victoria
Chung, Esther O.
LeMasters, Katherine
Andrabi, Nafeesa
Bates, Lisa M.
Rahman, Atif
Sikander, Siham
Turner, Elizabeth L.
Maselko, Joanna

Year Published

2020

Volume Number

276

Pages

592-9

NIHMSID

NIHMS1614790

Reference ID

13108