Concordance of Haemoglobin A1c, Blood Pressure and C-Reactive Protein between Children and Their Parents in Chinese Households
2466.ris
—
Octet Stream,
1 kB (2,021 bytes)
Background: China has the world’s highest diabetes prevalence, which alongwith hypertension and inflammation continues to grow particularly among children.Little is known about the strength of the association of these cardiometabolic riskfactors between parents and their children; thus, the potential of household-based strategies to reduce risk is unknown
Objectives: The objective of the study is to examine the parent–child associationfor haemoglobin A1c (HbA1c), blood pressure (BP) and C-reactive protein (CRP) ina large, geographically diverse Chinese sample.
Methods: In 940 parent–child pairs (children aged 7–17 years) who participatedin the 2009 China Health and Nutrition Survey, we measured each individual’sHbA1c and CRP using fasting blood and BP. We used sex-specific random-effects linear regression to examine the parent–child association for these risk fac-tors, accounting for within-family clustering.Results:Child’s HbA1c was positively associated with parental HbA1c. Betacoefficients ranged from 0.06 (95% CI 0.03–0.12) for father–daughter to 0.43(95% CI 0.28–0.58) for mother–son pairs. We also detected a positive mother–daughter association for BP and positive father–child associations for CRP.
Conclusion: The statistically significant parent–child association for HbA1c, BPand CRP in Chinese families suggests that household-based interventions couldbe useful for confronting the high rates of diabetes, hypertension and inflammationin China.
JOUR
Dong, Fei
Howard, Annie Green
Herring, Amy H.
Adair, Linda S.
Thompson, Amanda L.
Popkin, Barry M.
Aiello, Allison E.
Zhang, Bing
Gordon-Larsen, Penny
2016
Pediatric Obesity
12
5
422-30
PMC5201443
2466