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Comparison of Child Adiposity Indices in Prediction of Hypertension in Early Adulthood

Fan, Hui; Zhu, Qi; Medrano-Gracia, Pau; & Zhang, Xingyu. (2019). Comparison of Child Adiposity Indices in Prediction of Hypertension in Early Adulthood. Journal of Clinical Hypertension, 21(12), 1858-1862.

Fan, Hui; Zhu, Qi; Medrano-Gracia, Pau; & Zhang, Xingyu. (2019). Comparison of Child Adiposity Indices in Prediction of Hypertension in Early Adulthood. Journal of Clinical Hypertension, 21(12), 1858-1862.

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We aimed to compare child body mass index (BMI) in prediction of hypertension in early adulthood with 4 other adiposity indices (waist circumference [WC], waist circumference-to-height ratio [WHtR], waist-to-hip ratio [WHR], and triceps skinfold [TSF]). The cohort from the China Health and Nutrition Survey 1993-2011 consisted of 1444 adults aged 18-36 years who were examined in childhood and early adulthood. Child adiposity indices and adult blood pressure (BP) were transformed into age-, sex-, and survey year-specific Z-scores. Adult hypertension was defined as BP >/=130/80 mm Hg as per the 2017 American College of Cardiology/American Heart Association guidelines. Adult hypertension prevalence was 32.9% during a mean follow-up of 10.1 years. Childhood BMI showed stronger correlation with adult BP than WHR and TSF (PS for difference <.05). Child BMI showed the better prediction of adult hypertension compared with WHtR, WHR, and TSF using area under the receiver operating characteristic curves (PS for difference <.05). Per SD change in the predictor, child BMI (relative risk [95% confidence interval], 1.11 [1.04-1.18]) and WC (1.12 [1.05-1.20]) were significantly associated with adult hypertension using covariate-adjusted Poisson models with robust standard errors. Child BMI performed equally or better compared with 4 other adiposity indices in predicting adult hypertension.




JOUR



Fan, Hui
Zhu, Qi
Medrano-Gracia, Pau
Zhang, Xingyu



2019


Journal of Clinical Hypertension

21

12

1858-1862










3013