New Add Health Data Release

The following data are now available to Add Health contract researchers.

Wave V Hepatic Injury
This file contains constructed measures designed to facilitate analysis and interpretation of hepatic injury based on venous blood collected via phlebotomy at the Wave V home exam.  Assay results for aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are available, as well as three semi-quantitative serum index assays – lipemia, hemolysis and icterus – to evaluate the possibility of interference with the AST or ALT assays.  Moreover, two constructed measures are available – the AST/ALT ratio and its classification. N=5,381

Wave V Neurodegeneration
This file contains constructed measures designed to facilitate analysis and interpretation of neurodegeneration based on venous blood collected via phlebotomy at the Wave V home exam.  Neurofilament light (NfL) and tau assay results are available, as well concentration type flags for each assay. N=5,381

Wave V Inflammation and Immune Function Addendum
This file contains additional constructed measures of inflammation including interleukin 1 beta (IL-1β), interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 10 (IL-10), tumor necrosis factor alpha (TNF-α) and cytomegalovirus (CMV).  Each measure has a corresponding concentration type flag or classification variable.  N=5,381

Wave V Renal Function Addendum
This file contains constructed measures designed to facilitate analysis and interpretation of renal function based on venous blood collected via phlebotomy at the Wave V home exam. Updated estimations of the glomerular filtration rate (GFR) based on 2021 guidelines are available using either the creatinine concentration or using both the creatinine and cystatin C concentrations.  The estimations of GFR have been calculated according to the 2021 NIDDK CKD-EPI guidelines.  Classifications of the new estimations according to both clinical and KDIGO guidelines are available as well.  N=5,381

Current Add Health investigators can log in to the CPC Data Portal and use the “Request More Data” button to order this dataset.

For more information on the CPC Data Portal, please visit the Frequently Asked Questions page.