Adherence to Nutrition-Based Cancer Prevention Guidelines and Breast, Prostate and Colorectal Cancer Risk in the MCC-Spain Case-Control Study

Citation

Romaguera, Dora; Gracia-Lavedan, Esther; Molinuevo, Amaia; de Batlle, Jordi; Mendez, Michelle A.; Moreno, Victor; Vidal, Carmen; Castello, Adela; Perez-Gomez, Beatriz; & Martin, Vicente, et al. (2017). Adherence to Nutrition-Based Cancer Prevention Guidelines and Breast, Prostate and Colorectal Cancer Risk in the MCC-Spain Case-Control Study. International Journal of Cancer, 141(1), 83-93.

Abstract

Prostate, breast and colorectal cancer are the most common tumours in Spain. The aim of the present study was to evaluate the association between adherence to nutrition-based guidelines for cancer prevention and prostate, breast and colorectal cancer, in the MCC-Spain case-control study. A total of 1,718 colorectal, 1,343 breast and 864 prostate cancer cases and 3,431 population-based controls recruited between 2007 and 2012, were included in the present study. The World Cancer Research Fund/American Institute for Cancer Research (WCRC/AICR) score based on six recommendations for cancer prevention (on body fatness, physical activity, foods and drinks that promote weight gain, plant foods, animal foods and alcoholic drinks; score range 0-6) was constructed. We used unconditional logistic regression analysis adjusting for potential confounders. One-point increment in the WCRF/AICR score was associated with 25% (95% CI 19-30%) lower risk of colorectal, and 15% (95% CI 7-22%) lower risk of breast cancer; no association with prostate cancer was detected, except for cases with a Gleason score >/=7 (poorly differentiated / undifferentiated tumours) (OR 0.87, 95% CI 0.76-0.99). These results add to the wealth of evidence indicating that a great proportion of common cancer cases could be avoided by adopting healthy lifestyle habits.

URL

http://dx.doi.org/10.1002/ijc.30722

Reference Type

Journal Article

Year Published

2017

Journal Title

International Journal of Cancer

Author(s)

Romaguera, Dora
Gracia-Lavedan, Esther
Molinuevo, Amaia
de Batlle, Jordi
Mendez, Michelle A.
Moreno, Victor
Vidal, Carmen
Castello, Adela
Perez-Gomez, Beatriz
Martin, Vicente
Molina, Antonio J.
Davila-Batista, Veronica
Dierssen-Sotos, Trinidad
Gomez-Acebo, Ines
Llorca, Javier
Guevara, Marcela
Castilla, Jesus
Urtiaga, Carmen
Llorens-Ivorra, Cristobal
Fernandez-Tardon, Guillermo
Tardon, Adonina
Lorca, Jose Andres
Marcos-Gragera, Rafael
Huerta, Jose Maria
Olmedo-Requena, Rocio
Jimenez-Moleon, Jose Juan
Altzibar, Jone M.
de Sanjose, Silvia
Pollan, Marina
Aragones, Nuria
Castano-Vinyals, Gemma
Kogevinas, Manolis
Amiano, Pilar