Citation
Garcia, Lorena; Lee, Anne; Zeki Al Hazzouri, Adina; Neuhaus, John M.; Moyce, Sally C.; Aiello, Allison E.; & Haan, Mary N. (2016). Influence of Neighbourhood Socioeconomic Position on the Transition to Type II Diabetes in Older Mexican Americans: The Sacramento Area Longitudinal Study on Aging. BMJ Open, 6(8), e010905. PMCID: PMC4985827Abstract
OBJECTIVE: To examine the influence of neighbourhood socioeconomic position (NSEP) on development of diabetes over time. DESIGN: A longitudinal cohort study. SETTING: The data reported were from the Sacramento Area Latino Study on Aging, a longitudinal study of the health of 1789 older Latinos.PARTICIPANTS: Community-dwelling older Mexican Americans residing in the Sacramento Metropolitan Statistical Area. MAIN OUTCOME: Multistate Markov regression were used to model transitions through four possible states over time: 1=normal; 2=pre-diabetic; 3=diabetic; and 4=death without diabetes.
RESULTS: At baseline, nearly 50% were non-diabetic, 17.5% were pre-diabetic and nearly 33% were diabetic. At the end of follow-up, there were a total of 824 people with type 2 diabetes. In a fully adjusted MSM regression model, among non-diabetics, higher NSEP was not associated with a transition to pre-diabetes. Among non-diabetics, higher NSEP was associated with an increased risk of diabetes (HR=1.66, 95% CI 1.14 to 2.42) and decreased risk of death without diabetes (HR: 0.56, 95% CI 0.33 to 0.96). Among pre-diabetics, higher NSEP was significantly associated with a transition to non-diabetic status (HR: 1.22, 95% CI 0.99 to 1.50). Adjusting for BMI, age, education, physical activity, smoking, alcohol consumption, medical insurance and nativity did not affect this relationship.
CONCLUSIONS: Our findings show that high NSEP poses higher risk of progression from normal to diabetes compared with a lower risk of death without diabetes. This work presents a possibility that these associations are modified by nativity or culture.
URL
http://dx.doi.org/10.1136/bmjopen-2015-010905Reference Type
Journal ArticleYear Published
2016Journal Title
BMJ OpenAuthor(s)
Garcia, LorenaLee, Anne
Zeki Al Hazzouri, Adina
Neuhaus, John M.
Moyce, Sally C.
Aiello, Allison E.
Haan, Mary N.