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Citation

Nazia, Nushrat; Ali, Mohammad; Jakariya, Md; Nahar, Quamrun; Yunus, Mohammad; & Emch, Michael E. (2018). Spatial and Population Drivers of Persistent Cholera Transmission in Rural Bangladesh: Implications for Vaccine and Intervention Targeting. Spatial and Spatio-Temporal Epidemiology, 24, 1-9. PMCID: PMC6693335

Abstract

We identify high risk clusters and measure their persistence in time and analyze spatial and population drivers of small area incidence over time. The geographically linked population and cholera surveillance data in Matlab, Bangladesh for a 10-year period were used. Individual level data were aggregated by local 250x250m communities. A retrospective space-time scan statistic was applied to detect high risk clusters. Generalized estimating equations were used to identify risk factors for cholera. We identified 10 high risk clusters, the largest of which was in the southern part of the study area where a smaller river flows into a large river. There is persistence of local spatial patterns of cholera and the patterns are related to both the population composition and ongoing spatial diffusion from nearby areas over time. This information suggests that targeting interventions to high risk areas would help eliminate locally persistent endemic areas.

URL

http://dx.doi.org/10.1016/j.sste.2017.09.001

Reference Type

Journal Article

Year Published

2018

Journal Title

Spatial and Spatio-Temporal Epidemiology

Author(s)

Nazia, Nushrat
Ali, Mohammad
Jakariya, Md
Nahar, Quamrun
Yunus, Mohammad
Emch, Michael E.

PMCID

PMC6693335

ORCiD

Emch - 0000-0003-2642-965X