Maternal Hematologic Changes during Pregnancy and the Effect of Iron Status on Preterm Delivery in a West Los Angeles Population

Citation

Siega-Riz, Anna Maria; Adair, Linda S.; & Hobel, Calvin J. (1998). Maternal Hematologic Changes during Pregnancy and the Effect of Iron Status on Preterm Delivery in a West Los Angeles Population. American Journal of Perinatology, 15(9), 515-522.

Abstract

This study was conducted to document the prevalence of anemia and high hematocrit during pregnancy and examine their effect on delivering preterm in a predominantly Hispanic population. The sample consisted of women receiving prenatal care from the public health clinics in the West Los Angeles from 1983 to 1986 (n = 7589). Multivariate logistic regression was used to isolate the role of anemia and high hematocrit from other factors that may influence birth outcome. The prevalence of anemia was approximately 9% at the initiation of prenatal care and at 28-32 weeks' gestation. Only anemia at 28-32 weeks was significantly associated with a preterm birth, even after adjusting for several confounders [Adjusted Odds Ratio (AOR) 1.83 95% Cl = 1.21, 2.77]. A high hematocrit that occurred in 9.6% of the population at 28-32 weeks was inversely associated with a preterm birth (AOR 0.78, 95% Cl = 0.44, 1.39). There was little differentiation of these risk factors when analyzing the etiological pathways of a preterm birth. These results indicate for the first time in a predominantly Hispanic population that despite routine iron supplementation, anemia still occurs in pregnant women and it can predict a preterm delivery.

URL

http://dx.doi.org/10.1055/s-2007-993976

Reference Type

Journal Article

Year Published

1998

Journal Title

American Journal of Perinatology

Author(s)

Siega-Riz, Anna Maria
Adair, Linda S.
Hobel, Calvin J.

ORCiD

Adair - 0000-0002-3670-8073
Siega-Riz - 0000-0002-1303-4248