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Sleep and Neurocognitive Decline in the Hispanic Community Health Study/Study of Latinos

Citation

Ramos, Alberto R.; Tarraf, Wassim; Wu, Benson; Redline, Susan S.; Cai, Jianwen; Daviglus, Martha L.; Gallo, Linda C.; Mossavar-Rahmani, Yasmin; Perreira, Krista M.; & Zee, Phyllis C., et al. (2020). Sleep and Neurocognitive Decline in the Hispanic Community Health Study/Study of Latinos. Alzheimer's & Dementia, 16(2), 305-315. PMCID: PMC7007834

Abstract

INTRODUCTION: To determine if sleep-disordered breathing (SDB), daytime sleepiness, insomnia, and sleep duration predict seven-year neurocognitive decline in US Hispanics/Latinos (N = 5247).
METHODS: The exposures were baseline SDB, daytime sleepiness, insomnia, and sleep duration. The outcomes were change in episodic learning and memory (B-SEVLT-Sum and SEVLT-Recall), language (word fluency [WF]), processing speed (Digit Symbol Substitution), and a cognitive impairment screener (Six-item Screener [SIS]).
RESULTS: Mean age was 63 +/- 8 years, with 55% of the population being female with 7.0% Central American, 24.5% Cuban, 9.3% Dominican, 35.9% Mexican, 14.4% Puerto Rican, and 5.1% South American background. Long sleep (>9 hours), but not short sleep (<6 hours), was associated with decline (standard deviation units) in episodic learning and memory (betaSEVLT-Sum = -0.22 [se = 0.06]; P < .001; betaSEVLT-Recall = -0.13 [se = 0.06]; P < .05), WF (betaWF = -0.20 [se = 0.06]; P < .01), and SIS (betaSIS = -0.16 [se = 0.06]; P < .01), but not processing speed, after adjusting for covariates. SDB, sleepiness, and insomnia were not associated with neurocognitive decline.
CONCLUSION: Long sleep duration predicted seven-year cognitive decline.

URL

http://dx.doi.org/10.1016/j.jalz.2019.08.191

Reference Type

Journal Article

Article Type

Regular

Year Published

2020

Journal Title

Alzheimer's & Dementia

Author(s)

Ramos, Alberto R.
Tarraf, Wassim
Wu, Benson
Redline, Susan S.
Cai, Jianwen
Daviglus, Martha L.
Gallo, Linda C.
Mossavar-Rahmani, Yasmin
Perreira, Krista M.
Zee, Phyllis C.
Zeng, Donglin
Gonzalez, Hector M.

PMCID

PMC7007834

Data Set/Study

Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Continent/Country

United States of America

State

Nonspecific

Race/Ethnicity

Hispanic/Latinx