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Association between Maternal Periconceptional Alcohol Consumption and Neural Tube Defects: Findings from the National Birth Defects Prevention Study, 1997-2011

Citation

Louden, Adia R.; Suhl, Jonathan; Kancherla, Vijaya; Caspers Conway, Kristin M.; Makelarski, Jennifer A.; Howley, Meredith M.; Hoyt, Adrienne T.; Olney, Richard S.; Olshan, Andrew F.; & Romitti, Paul A., et al. (2020). Association between Maternal Periconceptional Alcohol Consumption and Neural Tube Defects: Findings from the National Birth Defects Prevention Study, 1997-2011. Birth Defects Research, 112(5), 427-39. PMCID: PMC7099604

Abstract

BACKGROUND: Neural tube defects (NTD)s are common birth defects with a multifactorial etiology. Findings from human studies examining environmental (non-inherited) exposures tend to be inconclusive. In particular, although animal studies of alcohol exposure and NTDs support its teratogenic potential, human studies are equivocal. Using data from the National Birth Defects Prevention Study (NBDPS), associations between maternal periconceptional (1 month before through 1 month after conception) alcohol consumption and NTDs in offspring were examined.

URL

http://dx.doi.org/10.1002/bdr2.1656

Reference Type

Journal Article

Journal Title

Birth Defects Research

Author(s)

Louden, Adia R.
Suhl, Jonathan
Kancherla, Vijaya
Caspers Conway, Kristin M.
Makelarski, Jennifer A.
Howley, Meredith M.
Hoyt, Adrienne T.
Olney, Richard S.
Olshan, Andrew F.
Romitti, Paul A.
the National Birth Defects Prevention Study

Year Published

2020

Volume Number

112

Issue Number

5

Pages

427-39

PMCID

PMC7099604

Reference ID

13062