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Assessment of Interactions between 205 Breast Cancer Susceptibility Loci and 13 Established Risk Factors in Relation to Breast Cancer Risk, in the Breast Cancer Association Consortium

Citation

Kapoor, Pooja Middha; Lindström, Sara; Behrens, Sabine; Wang, Xiaoliang; Michailidou, Kyriaki; Bolla, Manjeet K.; Wang, Qin; Dennis, Joe G.; Dunning, Alison M.; & Pharoah, Paul D. P., et al. (2020). Assessment of Interactions between 205 Breast Cancer Susceptibility Loci and 13 Established Risk Factors in Relation to Breast Cancer Risk, in the Breast Cancer Association Consortium. International Journal of Epidemiology, 49(1), 216-30. PMCID: PMC7426027

Abstract

BACKGROUND: Previous gene-environment interaction studies of breast cancer risk have provided sparse evidence of interactions. Using the largest available dataset to date, we performed a comprehensive assessment of potential effect modification of 205 common susceptibility variants by 13 established breast cancer risk factors, including replication of previously reported interactions.

URL

https://doi.org/10.1093/ije/dyz193

Reference Type

Journal Article

Journal Title

International Journal of Epidemiology

Author(s)

Kapoor, Pooja Middha
Lindström, Sara
Behrens, Sabine
Wang, Xiaoliang
Michailidou, Kyriaki
Bolla, Manjeet K.
Wang, Qin
Dennis, Joe G.
Dunning, Alison M.
Pharoah, Paul D. P.
Schmidt, Marjanka K.
Kraft, Peter
García-Closas, Montserrat
Easton, Douglas F.
Milne, Roger L.
Chang-Claude, Jenny on behalf of Breast Cancer Association Consortium [Olshan, Andrew F. Member],

Year Published

2020

Volume Number

49

Issue Number

1

Pages

216-30

PMCID

PMC7426027

Reference ID

13066