Citation
Pichardo, Catherine M.; Pichardo, Margaret S.; Gallo, Linda C.; Talavera, Gregory A.; Chambers, Earle C.; Sanchez-Johnsen, Lisa A. P.; Pirzada, Amber; Roy, Amanda L.; Rodriguez, Carmen; & Castañeda, Sheila F., et al. (2023). Association of Neighborhood Segregation with 6-Year Incidence of Metabolic Syndrome in the Hispanic Community Health Study/ Study of Latinos. Annals of Epidemiology, 78, 1-8. PMCID: PMC10127516Abstract
OBJECTIVE: Examine the association between neighborhood segregation and 6-year incident metabolic syndrome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).DESIGN: Prospective cohort of adults residing in Miami, Chicago, the Bronx, and San Diego. The analytic sample included 6,710 participants who did not have metabolic syndrome (MetSyn) at baseline.
MEASURES: The evenness and exposure dimensions of neighborhood segregation, based on the Gini and Isolation indices, respectively, were categorized into quintiles (Q). Racialized economic concentration was measured with the Index of Concentration at the Extremes (continuously and quintiles).
RESULTS: Exposure, but not evenness, was associated with higher disease odds (Q1 (lower segregation) vs. Q4, OR=1.53, 95% CI=1.08-2.17; Q5, OR=2.29, 95% CI =1.49-3.52). Economic concentration (continuous OR=0.87, 95% CI=0.77-0.98), racial concentration (Q1 (greater concentration) vs. Q2 OR=0.75, 95% CI=0.54-1.04; Q3 OR=0.68, 95% CI=0.44-1.05; Q4 OR=0.68, 95% CI=0.45-1.01; Q5 OR=0.64, 95% CI=0.42-0.98), and racialized economic concentration (i.e., higher SES non-Hispanic White, 0.86, 95% CI=0.76-0.98) were associated with lower disease odds.
CONCLUSIONS AND RELEVANCE: Hispanics/Latino adults residing in neighborhoods with high segregation had higher risk of incident metabolic syndrome compared to those residing in neighborhoods with low segregation. Research is needed to identify the mechanisms that link segregation to poor metabolic health.
URL
http://dx.doi.org/10.1016/j.annepidem.2022.11.003Reference Type
Journal ArticleYear Published
2023Journal Title
Annals of EpidemiologyAuthor(s)
Pichardo, Catherine M.Pichardo, Margaret S.
Gallo, Linda C.
Talavera, Gregory A.
Chambers, Earle C.
Sanchez-Johnsen, Lisa A. P.
Pirzada, Amber
Roy, Amanda L.
Rodriguez, Carmen
Castañeda, Sheila F.
Durazo-Arvizu, Ramon A.
Perreira, Krista M.
Garcia, Tanya P.
Allison, Matthew A.
Carlson, Jordan A.
Daviglus, Martha L.
Plascak, Jesse J.