Citation
Poveda, Natalia E.; Adair, Linda S.; Martorell, Reynaldo; Patel, Shivani A.; Ramirez-Zea, Manuel; Bhargava, Santosh K.; Bechayda, Sonny A.; Carba, Delia B.; Kroker-Lobos, Maria F.; & Horta, Bernardo L., et al. (2023). Growth Patterns in Childhood and Adolescence and Adult Body Composition: A Pooled Analysis of Birth Cohort Studies from Five Low and Middle-Income Countries (COHORTS Collaboration). BMJ Open, 13(3), e068427. PMCID: PMC10030655Abstract
OBJECTIVE: We examined associations among serial measures of linear growth and relative weight with adult body composition.DESIGN: Secondary data analysis of prospective birth cohort studies.
SETTINGS: Six birth cohorts from Brazil, Guatemala, India, the Philippines and South Africa.
PARTICIPANTS: 4173 individuals followed from birth to ages 22-46 years with complete and valid weight and height at birth, infancy, childhood and adolescence, and body composition in adult life.
EXPOSURES: Birth weight and conditional size (standardised residuals of height representing linear growth and of relative weight representing weight increments independent of linear size) in infancy, childhood and adolescence.
PRIMARY OUTCOME MEASURES: Body mass index, fat mass index (FMI), fat-free mass index (FFMI), fat mass/fat-free mass ratio (FM/FFM), and waist circumference in young and mid-adulthood.
RESULTS: In pooled analyses, a higher birth weight and relative weight gains in infancy, childhood and adolescence were positively associated with all adult outcomes. Relative weight gains in childhood and adolescence were the strongest predictors of adult body composition (
URL
http://dx.doi.org/10.1136/bmjopen-2022-068427Reference Type
Journal ArticleYear Published
2023Journal Title
BMJ OpenAuthor(s)
Poveda, Natalia E.Adair, Linda S.
Martorell, Reynaldo
Patel, Shivani A.
Ramirez-Zea, Manuel
Bhargava, Santosh K.
Bechayda, Sonny A.
Carba, Delia B.
Kroker-Lobos, Maria F.
Horta, Bernardo L.
Lima, Natália P.
Mazariegos, Mónica
Menezes, Ana Maria B.
Norris, Shane A.
Nyati, Lukhanyo H.
Richter, Linda M.
Sachdev, Harshpal Singh
Wehrmeister, Fernando C.
Stein, Aryeh D.
Article Type
RegularPMCID
PMC10030655Data Set/Study
Consortium of Health-Oriented Research in Transitioning Societies (COHORTS)Continent/Country
LMICsBrazil
Guatemala
India
Philippines
South Africa