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Workshop to Identify Critical Windows of Exposure for Children’s Health: Cancer Work Group Summary

Citation

Olshan, Andrew F.; Anderson, Lucy; Roman, Eve; Fear, Nicola; Wolff, Mary S.; Whyatt, Robin; Vu, Vanessa; Diwan, Bhalchand A.; & Potischman, Nancy (2000). Workshop to Identify Critical Windows of Exposure for Children's Health: Cancer Work Group Summary. Environmental Health Perspectives, 108(Suppl. 3), 595-7. PMCID: PMC1637821

Abstract

We considered whether there are discrete windows of vulnerability in the development of cancer and which time periods may be of the greatest importance. Cancer was considered broadly, including cancers in childhood as well as adult cancers that may have an in utero or childhood origin. We concluded that there was evidence from animal and epidemiologic studies for causal relationships for preconceptional, in utero, and childhood exposures and cancer occurrence in children and adults. However, the evidence is incomplete and all relevant critical windows may not have been identified. The comprehensive evaluation of the relative importance of specific time windows of exposure is limited. Improvements in the design of epidemiologic studies and additional animal studies of mechanisms are warranted.

URL

http://dx.doi.org/10.1289/ehp.00108s3595

Notes

ProCite field[28]: PMC1637821

Reference Type

Journal Article

Journal Title

Environmental Health Perspectives

Author(s)

Olshan, Andrew F.
Anderson, Lucy
Roman, Eve
Fear, Nicola
Wolff, Mary S.
Whyatt, Robin
Vu, Vanessa
Diwan, Bhalchand A.
Potischman, Nancy

Year Published

2000

Volume Number

108

Issue Number

Suppl. 3

Pages

595-7

PMCID

PMC1637821

Reference ID

1587