Menu Close

Reconciling Animal and Human Data in a Cancer Risk Assessment of Acrylonitrile

Citation

Schulz, Mark R.; Hertz-Picciotto, Irva; Todd, Lori; & Ball, Louise M. (2001). Reconciling Animal and Human Data in a Cancer Risk Assessment of Acrylonitrile. Scandinavian Journal of Work, Environment and Health, 27(1), 14-20.

Abstract

Objectives: Bioassays of rats exposed to acrylonitrile have consistently detected an elevated incidence of central nervous system (CNS) cancer. In contrast, epidemiologic studies have not found a statistically stable increase in CNS cancer mortality. The purpose of this paper is to examine whether or not CNS cancers predicted from the most appropriate inhalation bioassay in rats are consistent with CNS cancers observed in 3 recent, large epidemiologic studies.

URL

http://dx.doi.org/10.5271/sjweh.582

Reference Type

Journal Article

Journal Title

Scandinavian Journal of Work, Environment and Health

Author(s)

Schulz, Mark R.
Hertz-Picciotto, Irva
Todd, Lori
Ball, Louise M.

Year Published

2001

Volume Number

27

Issue Number

1

Pages

14-20

Reference ID

1656