Fine Particulate Matter and Incident Coronary Heart Disease Events up to 10 Years of Follow-Up among Deepwater Horizon Oil Spill Workers

Download as .RIS

Citation

Chen, Dazhe; Sandler, Dale P.; Keil, Alexander P.; Heiss, Gerardo M.; Whitsel, Eric A.; Pratt, Gregory C.; Stewart, Patricia A.; Stenzel, Mark R.; Groth, Caroline P.; & Banerjee, Sudipto, et al. (2023). Fine Particulate Matter and Incident Coronary Heart Disease Events up to 10 Years of Follow-Up among Deepwater Horizon Oil Spill Workers. Environmental Research, 217, 114841. PMCID: PMC9825646

Abstract

BACKGROUND: During the 2010 Deepwater Horizon (DWH) disaster, in-situ burning and flaring were conducted to remove oil from the water. Workers near combustion sites were potentially exposed to burning-related fine particulate matter (PM(2.5)). Exposure to PM(2.5) has been linked to increased risk of coronary heart disease (CHD), but no study has examined the relationship among oil spill workers.
OBJECTIVES: To investigate the association between estimated PM(2.5) from burning/flaring of oil/gas and CHD risk among the DWH oil spill workers.
METHODS: We included workers who participated in response and cleanup activities on the water during the DWH disaster (N = 9091). PM(2.5) exposures were estimated using a job-exposure matrix that linked modelled PM(2.5) concentrations to detailed DWH spill work histories provided by participants. We ascertained CHD events as the first self-reported physician-diagnosed CHD or a fatal CHD event that occurred after each worker's last day of burning exposure. We estimated hazard ratios (HR) and 95% confidence intervals (95%CI) for the associations between categories of average or cumulative daily maximum PM(2.5) exposure (versus a referent category of water workers not near controlled burning) and subsequent CHD. We assessed exposure-response trends by examining continuous exposure parameters in models.
RESULTS: We observed increased CHD hazard among workers with higher levels of average daily maximum exposure (low vs. referent: HR = 1.26, 95% CI: 0.93, 1.70; high vs. referent: HR = 2.11, 95% CI: 1.08, 4.12; per 10 

URL

http://dx.doi.org/10.1016/j.envres.2022.114841

Reference Type

Journal Article

Year Published

2023

Journal Title

Environmental Research

Author(s)

Chen, Dazhe
Sandler, Dale P.
Keil, Alexander P.
Heiss, Gerardo M.
Whitsel, Eric A.
Pratt, Gregory C.
Stewart, Patricia A.
Stenzel, Mark R.
Groth, Caroline P.
Banerjee, Sudipto
Huynh, Tran B.
Edwards, Jessie K.
Jackson, W. Braxton 2nd
Engeda, Joseph C.
Kwok, Richard K.
Werder, Emily J.
Lawrence, Kaitlyn G.
Engel, Lawrence S.

Article Type

Regular

PMCID

PMC9825646

Data Set/Study

Gulf Long-Term Follow-up Study (GuLF Study)

Continent/Country

United States of America

State

Nonspecific

Race/Ethnicity

Black
White
Hispanic/Latinx

ORCiD

Edwards, J -0000-0002-1741-335X