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Preeclampsia and Cerebral Palsy in Low-Birth-Weight and Preterm Infants: Implications for the Current “Ischemic Model” of Preeclampsia

Citation

Xu, Xiong; Saunders, L. Duncan; Wang, Fu-Lin; Davidge, Sandra T.; & Buekens, Pierre (2001). Preeclampsia and Cerebral Palsy in Low-Birth-Weight and Preterm Infants: Implications for the Current "Ischemic Model" of Preeclampsia. Hypertension in Pregnancy, 20(1), 1-13.

Abstract

Objective: One of the prevailing hypotheses for the pathogenesis of preeclampsia is the "ischemic model." It assumes that reduced uteroplacental perfusion is the primary step and the point of convergence of diverse pathogenic processes in the development of preeclampsia. One might expect a fetus under such "ischemic conditions" to be at an increased risk of later development of cerebral palsy (CP). The objective of this study was to test the hypothesis that maternal preeclampsia increases the risk of CP in preterm and low-birth-weight infants.

URL

http://dx.doi.org/10.1081/PRG-100104167

Reference Type

Journal Article

Journal Title

Hypertension in Pregnancy

Author(s)

Xu, Xiong
Saunders, L. Duncan
Wang, Fu-Lin
Davidge, Sandra T.
Buekens, Pierre

Year Published

2001

Volume Number

20

Issue Number

1

Pages

1-13

Reference ID

1792