Citation
Hatcher, Juliet L.; Baris, Dalsu; Olshan, Andrew F.; Inskip, Peter D.; Savitz, David A.; Swanson, G. Marie; Pottern, Linda M.; Greenberg, Raymond S.; Schwartz, Ann G.; & Schoenberg, Janet B., et al. (2001). Diagnostic Radiation and the Risk of Multiple Myeloma (United States). Cancer Causes & Control, 12(8), 755-761.Abstract
Objective: To evaluate the relationship between cumulative lifetime exposure to diagnostic radiation and the risk of multiple myeloma using data from a large, multi-center, population-based case–control study.Methods: Study subjects included a total of 540 cases with newly diagnosed multiple myeloma and 1998 frequency-matched population controls living in three areas of the United States (Georgia, Michigan, New Jersey). Information on exposure to diagnostic X-rays was obtained by personal interview.
Results: No association was found between case–control status and the total number of reported diagnostic X-rays of any type (odds ratio (OR) for 20 or more compared to less than 5 X-rays = 0.9, 95% confidence interval (95% CI) = 0.7–1.2). There was no evidence of an excess risk of multiple myeloma among individuals who reported exposure to 10 or more diagnostic X-rays that impart a relatively high radiation dose to the bone marrow, as compared to individuals reporting no such exposures (OR 0.7, 95% CI 0.4–1.3).
Conclusions: These data suggest that exposure to diagnostic X-rays has a negligible impact, if any, on risk of developing multiple myeloma.
URL
http://dx.doi.org/10.1023/A:1011205908596Reference Type
Journal ArticleYear Published
2001Journal Title
Cancer Causes & ControlAuthor(s)
Hatcher, Juliet L.Baris, Dalsu
Olshan, Andrew F.
Inskip, Peter D.
Savitz, David A.
Swanson, G. Marie
Pottern, Linda M.
Greenberg, Raymond S.
Schwartz, Ann G.
Schoenberg, Janet B.
Brown, Linda Morris