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Risk of Atherosclerosis: Interaction of Smoking and Glutathione S-Transferase Genes

Citation

Olshan, Andrew F.; Li, Rongling L.; Pankow, James S.; Bray, Molly S.; Tyroler, Herman A.; Chambless, Lloyd E.; Boerwinkle, Eric A.; Pittman, Gary S.; & Bell, Douglas A. (2003). Risk of Atherosclerosis: Interaction of Smoking and Glutathione S-Transferase Genes. Epidemiology, 14(3), 321-7.

Abstract

Background: Cigarette smoking is a well-known risk factor for not only incident events of coronary heart disease, but also preclinical atherosclerosis. Enzymes including glutathione S-transferase mu (GSTM1) and theta (GSTT1) are involved in the metabolism of tobacco smoke chemicals and are expressed in human vessels and smooth muscle cells.

URL

http://dx.doi.org/10.1097/01.EDE.0000059229.74889.CF

Reference Type

Journal Article

Journal Title

Epidemiology

Author(s)

Olshan, Andrew F.
Li, Rongling L.
Pankow, James S.
Bray, Molly S.
Tyroler, Herman A.
Chambless, Lloyd E.
Boerwinkle, Eric A.
Pittman, Gary S.
Bell, Douglas A.

Year Published

2003

Volume Number

14

Issue Number

3

Pages

321-7

Reference ID

2136