Discovery of Genetic Susceptibility Factors for Human Birth Defects: An Opportunity for a National Agenda

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Citation

Olshan, Andrew F.; Hobbs, Charlotte A.; & Shaw, Gary M. (2011). Discovery of Genetic Susceptibility Factors for Human Birth Defects: An Opportunity for a National Agenda. American Journal of Medical Genetics, Part A, 155(8), 1794-1797.

Abstract

A recent workshop highlighted the current challenges and new opportunities for studying the role of genetic factors in the etiology of human birth defects. The workshop provided a series of recommendations pertaining to the use of animal models, key elements of population-based designs, the need for national collaborative projects, biorepositories, and consortia, investigation of new types of structural genetic variants, examination of gene–exposure interactions, and a strategy for gene variant discovery. A key reason to hold the recent workshop and contribute this concise communication to the literature is to draw attention to and initiate action toward advancing discoveries about the genetic etiologies of birth defects.

URL

http://dx.doi.org/10.1002/ajmg.a.34103

Reference Type

Journal Article

Year Published

2011

Journal Title

American Journal of Medical Genetics, Part A

Author(s)

Olshan, Andrew F.
Hobbs, Charlotte A.
Shaw, Gary M.

ORCiD

Olshan - 0000-0001-9115-5128