HPTN 062: A Feasibility and Acceptability Pilot Intervention to Reduce HIV Transmission Risk Behaviors among Individuals with Acute and Early HIV Infection in Lilongwe, Malawi

Citation

Corneli, Amy L.; Pettifor, Audrey E.; Kamanga, Gift; Golin, Carol Elaine; McKenna, Kevin; Ou, San-San; Hamela, Gloria; Massa, Cecilia; Martinson, Francis E. A.; & Tharaldson, Jenae, et al. (2014). HPTN 062: A Feasibility and Acceptability Pilot Intervention to Reduce HIV Transmission Risk Behaviors among Individuals with Acute and Early HIV Infection in Lilongwe, Malawi. AIDS and Behavior, 18(9), 1785-1800. PMCID: PMC4183128

Abstract

Acute HIV infection (AHI) is a relatively brief period of time when individuals are highly infectious and the opportunity to intervene to prevent forward transmission is extremely limited. HPTN 062 partnered with CHAVI 001 to evaluate the feasibility and acceptability of a motivational interviewing (MI)-based counseling intervention to reduce HIV-transmission risk behaviors among individuals with acute and early HIV infection in Lilongwe, Malawi. Participants were randomized to receive either (1) brief education sessions about HIV and AHI; or (2) the same brief education sessions plus an MI-based counseling intervention called Uphungu Wanga. Although Uphungu Wanga was determined to be feasible and acceptable, few major differences existed between the two arms with regard to acceptability, feasibility, and self-reported sexual behaviors. We therefore conclude that an additional MI-based counseling intervention may not be needed during the short period of AHI. Instead, we recommend that individuals with AHI receive frequent, but brief, counseling immediately after diagnosis and then transition to receiving counseling at less frequent intervals until they can initiate antiretroviral therapy. Other recommendations are provided.

URL

http://dx.doi.org/10.1007/s10461-014-0707-1

Reference Type

Journal Article

Year Published

2014

Journal Title

AIDS and Behavior

Author(s)

Corneli, Amy L.
Pettifor, Audrey E.
Kamanga, Gift
Golin, Carol Elaine
McKenna, Kevin
Ou, San-San
Hamela, Gloria
Massa, Cecilia
Martinson, Francis E. A.
Tharaldson, Jenae
Hilgenberg, Deborah
Yu, Xuesong
Chege, Wairimu
Hoffman, Irving F.
The HPTN 062 Study Team,

PMCID

PMC4183128

ORCiD

Pettifor - 0000-0002-3387-0817