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Skin Microbiota: Microbial Community Structure and Its Potential Association with Health and Disease

Citation

Rosenthal, Mariana; Goldberg, Deborah; Aiello, Allison E.; Larson, Elaine L.; & Foxman, Betsy (2011). Skin Microbiota: Microbial Community Structure and Its Potential Association with Health and Disease. Infection, Genetics and Evolution, 11(5), 839-848. PMCID: PMC3114449

Abstract

Skin, the largest human organ, is a complex and dynamic ecosystem inhabited by a multitude of microorganisms. Host demographics and genetics, human behavior, local and regional environmental characteristics, and transmission events may all potentially drive human skin microbiota variability, resulting in an alteration of microbial community structure. This alteration may have important consequences regarding health and disease outcomes among individuals. More specifically, certain diversity patterns of human microbiota may be predictive or diagnostic of disease. The purpose of this review is to briefly describe the skin microbiota, outline the potential determining factors driving its variability, posit the likelihood of an association between the resulting microbial community structure on the skin with disease outcomes among individuals, and finally, to present some challenges and implications for studying the skin microbiota.

URL

http://dx.doi.org/10.1016/j.meegid.2011.03.022

Reference Type

Journal Article

Year Published

2011

Journal Title

Infection, Genetics and Evolution

Author(s)

Rosenthal, Mariana
Goldberg, Deborah
Aiello, Allison E.
Larson, Elaine L.
Foxman, Betsy

PMCID

PMC3114449