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The Authors Reply


Wyss, Annah B.; Hashibe, Mia; Lee, Yuan-Chin Amy; Chuang, Shu-Chun; Muscat, Joshua E.; Chen, Chu; Schwartz, Stephen M.; Smith, Elaine; Zhang, Zuo-Feng; & Morgenstern, Hal, et al. (2017). The Authors Reply. American Journal of Epidemiology, 186(5), 625-626. PMCID: PMC6279081


We appreciate the opportunity to respond to the letter by Dr. Rodu (1). In his letter, Rodu asks whether the female head and neck cancer (HNC) cases who used snuff were from the southern United States while the male HNC cases who used snuff were from throughout the United States. In response to this question, we have now performed analyses stratified by sex (female and male) and by region (southern United States and non–southern United States). The following International Head and Neck Cancer Epidemiology (INHANCE) studies or centers (2) were included in the “southern United States” stratum: Houston, Texas; North Carolina (1994–1997); North Carolina (2002–2006); and the Atlanta, Georgia, center of the US Multicenter Study. All other US studies or centers were included in the “non–southern United States” stratum: Seattle, Washington; Iowa; Los Angeles, California; Baltimore, Maryland; New York, New York (Memorial Sloan Kettering Cancer Center); New York State (multicenter); and the Los Angeles, California; New Jersey; and Santa Clara/San Mateo counties, California, centers of the US Multicenter Study.


Reference Type

Journal Article

Year Published


Journal Title

American Journal of Epidemiology


Wyss, Annah B.
Hashibe, Mia
Lee, Yuan-Chin Amy
Chuang, Shu-Chun
Muscat, Joshua E.
Chen, Chu
Schwartz, Stephen M.
Smith, Elaine
Zhang, Zuo-Feng
Morgenstern, Hal
Wei, Qingyi
Li, Guojun
Kelsey, Karl T.
Winn, Deborah M.
Gillison, Maura L.
Zevallos, Jose P.
Boffetta, Paolo
Olshan, Andrew F.