Breast Cancer Treatment Delays by Socioeconomic and Health Care Access Latent Classes in Black and White Women

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Citation

Emerson, Marc A.; Golightly, Yvonne M.; Aiello, Allison E.; Reeder-Hayes, Katherine E.; Tan, Xianming; Maduekwe, Ugwuji; Johnson-Thompson, Marian; Olshan, Andrew F.; & Troester, Melissa A. (2020). Breast Cancer Treatment Delays by Socioeconomic and Health Care Access Latent Classes in Black and White Women. Cancer, 126(22), 4957-4966. PMCID: PMC7789230

Abstract

BACKGROUND: Breast cancer mortality is higher for Black and younger women. This study evaluated 2 possible contributors to disparities-time to treatment and treatment duration-by race and age.
METHODS: Among 2841 participants with stage I-III disease in the Carolina Breast Cancer Study, we identified groups of women with similar patterns of socioeconomic status (SES), access to care, and tumor characteristics using latent class analysis. We then evaluated latent classes in association with treatment delay (initiation >60 days after diagnosis) and treatment duration (in quartiles by treatment modality).
RESULTS: Thirty-two percent of younger Black women were in the highest quartile of treatment duration (versus 22% of younger White women). Black women experienced a higher frequency of delayed treatment (adjusted relative frequency difference [RFD], 5.5% [95% CI, 3.2%-7.8%]) and prolonged treatment duration (RFD, 8.8% [95% CI, 5.7%-12.0%]). Low SES was significantly associated with treatment delay among White women (RFD, 3.5% [95% CI, 1.1%-5.9%]), but treatment delay was high at all levels of SES in Black women (eg, 11.7% in high SES Black women compared with 10.6% and 6.7% among low and high SES White women, respectively). Neither SES nor access to care classes were significantly associated with delayed initiation among Black women, but both low SES and more barriers were associated with treatment duration across both groups.
CONCLUSIONS: Factors that influence treatment timeliness persist throughout the care continuum, with prolonged treatment duration being a sensitive indicator of differences by race, SES, and care barriers.

URL

http://dx.doi.org/10.1002/cncr.33121

Reference Type

Journal Article

Year Published

2020

Journal Title

Cancer

Author(s)

Emerson, Marc A.
Golightly, Yvonne M.
Aiello, Allison E.
Reeder-Hayes, Katherine E.
Tan, Xianming
Maduekwe, Ugwuji
Johnson-Thompson, Marian
Olshan, Andrew F.
Troester, Melissa A.

Article Type

Regular

PMCID

PMC7789230

Data Set/Study

Carolina Breast Cancer Study (CBCS)

Continent/Country

United States of America

State

Nonspecific

Race/Ethnicity

Black

Sex/Gender

Women

ORCiD

Olshan - 0000-0001-9115-5128
Aiello - 0000-0001-7029-2537