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Treatment of Persistent Postpartum HELLP Syndrome with Plasmapheresis

Citation

Katz, Vern L.; Watson, William J.; Thorp, John M., Jr.; Hansen, Wendy; & Bowes, Watson A., Jr. (1992). Treatment of Persistent Postpartum HELLP Syndrome with Plasmapheresis. American Journal of Perinatology, 9(2), 120-122.

Abstract

Thrombocytopenia, associated with microangiopathic disease, is one characteristic of severe preeclampsia. Thrombocytopenia and intravascular hemolysis usually resolve by postpartum days 4 to 5. When thrombocytopenia secondary to microangiopathic disease persists, plasmapheresis may be used to arrest and reverse the process. Three patients over a 24-month period were successfully treated with plasma exchange with fresh frozen plasma. Several investigators who have cared for patients with persistent thrombocytopenia associated with preeclampsia have concluded that early plasmapheresis may be useful therapy. Plasma exchange should also be considered as a therapeutic option when clinical deterioration occurs due to microangiopathic disease.

URL

http://dx.doi.org/10.1055/s-2007-994683

Reference Type

Journal Article

Year Published

1992

Journal Title

American Journal of Perinatology

Author(s)

Katz, Vern L.
Watson, William J.
Thorp, John M., Jr.
Hansen, Wendy
Bowes, Watson A., Jr.