Thorp, John M., Jr. (2016). BJOG Editor's Choice: Pre-Emptive Diagnosis and Outcomes. BJOG: An International Journal of Obstetrics & Gynaecology, 123(6)
Having just finished visiting my internist for an annual checkup and pondering whether or not to have my prostate specific antigen (PSA) level measured, I sat down to read the papers for this month's Editor's Choice. Given that World Ovarian Cancer Day occurs in the month of this issue, I had been encouraged to consider an ovarian cancer paper by Limm and colleagues on pages 1012–1020. In it they compare Type I, so-called indolent cancers that progress stepwise and slowly, with the faster growing Type II malignancies. Contrary to their hypothesis, the time of progression from symptom onset to diagnosis was the same despite faster growth and more advanced cancers at diagnosis with Type II neoplasms. This topples the case for screening with the hope that early detection will allow more women to avoid the morbidity and mortality associated with this lethal disease.
BJOG: An International Journal of Obstetrics & Gynaecology
Thorp, John M., Jr.