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Paraoxonase Polymorphism and Its Effect on Male Reproductive Outcomes among Chinese Pesticide Factory Workers

Citation

Padungtod, Chantana; Niu, Tianhua; Wang, Zhaoxi; Savitz, David A.; Christiani, David C.; Ryan, Louise M.; & Xu, Xiping (1999). Paraoxonase Polymorphism and Its Effect on Male Reproductive Outcomes among Chinese Pesticide Factory Workers. American Journal of Industrial Medicine, 36(3), 379-87.

Abstract

Background: Serum paraoxonase has been associated with the metabolism of organophosphate pesticides in humans. Molecular analysis of the human paraoxonase gene (PON1) has revealed that Arg192 homozygotes have a greater detoxifying capability than Gln192 homozygotes. We examined the effects of PON1 genotypes on male reproductive outcomes and its interaction with exposure to organophosphate pesticides.

URL

http://dx.doi.org/10.1002/(sici)1097-0274(199909)36:3<379::aid-ajim5>3.0.co;2-8

Reference Type

Journal Article

Journal Title

American Journal of Industrial Medicine

Author(s)

Padungtod, Chantana
Niu, Tianhua
Wang, Zhaoxi
Savitz, David A.
Christiani, David C.
Ryan, Louise M.
Xu, Xiping

Year Published

1999

Volume Number

36

Issue Number

3

Pages

379-87

Reference ID

1511