CitationPadungtod, Chantana; Niu, Tianhua; Wang, Zhaoxi; Savitz, David A.; Christiani, David C.; Ryan, Louise M.; & Xu, Xiping (1999). Paraoxonase Polymorphism and Its Effect on Male Reproductive Outcomes among Chinese Pesticide Factory Workers. American Journal of Industrial Medicine, 36(3), 379-87.
AbstractBackground: Serum paraoxonase has been associated with the metabolism of organophosphate pesticides in humans. Molecular analysis of the human paraoxonase gene (PON1) has revealed that Arg192 homozygotes have a greater detoxifying capability than Gln192 homozygotes. We examined the effects of PON1 genotypes on male reproductive outcomes and its interaction with exposure to organophosphate pesticides.
Reference TypeJournal Article
Journal TitleAmerican Journal of Industrial Medicine
Savitz, David A.
Christiani, David C.
Ryan, Louise M.