Citation
Sikander, Siham; Ahmad, Ikhlaq; Bates, Lisa M.; Gallis, John A.; Hagaman, Ashley K; .; Turner, Elizabeth L.; Zaidi, Ahmed; Rahman, Atif; & Maselko, Joanna (2019). Cohort Profile: Perinatal Depression and Child Socio-Emotional Development: A Pregnancy-Birth Cohort Study in Rural Pakistan. BMJ Open, 9, e025644. PMCID: PMC6502044Abstract
Purpose: This is a prospective pregnancy–birth cohort designed to investigate the effects of depression on socioemotional development of children. Perinatal depression is a risk factor for poor child development and for many it has a recurring chronic course. Thus, the exposure to depression can continue through the early years of the child with detrimental developmental outcomes.Participants: Between October 2014 and February 2016, we recruited 1154 pregnant women from a rural subdistrict of Pakistan. Data include longitudinal and repeated measures of maternal psychosocial measures and child growth, cognitive and socioemotional measures. Follow-up include mother–child dyad assessments at 3rd, 6th, 12th, 24th and 36th months of child age. All these follow-ups are community based at the household level. We have competed baseline assessment.
Findings to date: Of the eligible dyads, we followed 885 (76.6%), 929 (91%) and 940 (93.3%) at 3, 6 and 12 months post-childbirth. We include a subsample mother–child dyad DNA and inflammatory biomarkers, 73 and 104, respectively.
Future plans: While we continue to do 24-month and 36-month follow-up assessments, we plan to follow these mother–child dyads up to the age of 7–8 years with some children being exposed to at least 1 year of school environment.
URL
http://dx.doi.org/10.1136/bmjopen-2018-025644Reference Type
Journal ArticleYear Published
2019Journal Title
BMJ OpenAuthor(s)
Sikander, SihamAhmad, Ikhlaq
Bates, Lisa M.
Gallis, John A.
Hagaman, Ashley K
.
Turner, Elizabeth L.
Zaidi, Ahmed
Rahman, Atif
Maselko, Joanna
PMCID
PMC6502044ORCiD
Maselko - 0000-0002-6270-8237Hagaman - 0000-0002-8016-1036