CitationDaniels, Julie L.; Olshan, Andrew F.; Pollock, Brad H.; Shah, Narayan R.; & Stram, Daniel O. (2002). Breast-Feeding and Neuroblastoma, USA and Canada. Cancer Causes & Control, 13(5), 401-405.
AbstractObjective: Researchers have suggested an inverse association between breast-feeding and risk of childhood cancer. We investigated the association between breast-feeding and neuroblastoma in a large case–control study in the United States and Canada.
Methods: Maternal reports of breast-feeding were compared among 393 children six months or older who had neuroblastoma and were identified through the Children's Cancer Group and the Pediatric Oncology Group and 376 age-matched controls identified by random-digit telephone dialing in a telephone interview case–control study.
Results: Children with neuroblastoma were less likely to have breast-fed than control children (odds ratio (OR) = 0.6; 95% confidence interval (CI) = 0.5–0.9). The association between breast-feeding and neuroblastoma increased with breast-feeding duration (0–3 months OR = 0.7, CI = 0.4–1.0; 13+ months OR = 0.5, CI = 0.3–0.9).
Conclusion: Breast-feeding was inversely associated with neuroblastoma and should be encouraged among healthy mothers. Additional research on possible mechanisms of this association may be warranted.
Reference TypeJournal Article
Journal TitleCancer Causes & Control
Author(s)Daniels, Julie L.
Olshan, Andrew F.
Pollock, Brad H.
Shah, Narayan R.
Stram, Daniel O.