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Breast-Feeding and Neuroblastoma, USA and Canada

Citation

Daniels, Julie L.; Olshan, Andrew F.; Pollock, Brad H.; Shah, Narayan R.; & Stram, Daniel O. (2002). Breast-Feeding and Neuroblastoma, USA and Canada. Cancer Causes & Control, 13(5), 401-5.

Abstract

Objective: Researchers have suggested an inverse association between breast-feeding and risk of childhood cancer. We investigated the association between breast-feeding and neuroblastoma in a large case–control study in the United States and Canada. Methods: Maternal reports of breast-feeding were compared among 393 children six months or older who had neuroblastoma and were identified through the Children's Cancer Group and the Pediatric Oncology Group and 376 age-matched controls identified by random-digit telephone dialing in a telephone interview case–control study. Results: Children with neuroblastoma were less likely to have breast-fed than control children (odds ratio (OR) = 0.6; 95% confidence interval (CI) = 0.5–0.9). The association between breast-feeding and neuroblastoma increased with breast-feeding duration (0–3 months OR = 0.7, CI = 0.4–1.0; 13+ months OR = 0.5, CI = 0.3–0.9). Conclusion: Breast-feeding was inversely associated with neuroblastoma and should be encouraged among healthy mothers. Additional research on possible mechanisms of this association may be warranted.

URL

http://dx.doi.org/10.1023/A:1015746701922

Reference Type

Journal Article

Journal Title

Cancer Causes & Control

Author(s)

Daniels, Julie L.
Olshan, Andrew F.
Pollock, Brad H.
Shah, Narayan R.
Stram, Daniel O.

Year Published

2002

Volume Number

13

Issue Number

5

Pages

401-5

Reference ID

1980