Citation
Pastore, Lisa M.; Savitz, David A.; Thorp, John M., Jr.; Koch, Gary G.; Hertz-Picciotto, Irva; & Irwin, Debra E. (1999). Predictors of Symptomatic Urinary Tract Infection after 20 Weeks' Gestation. Journal of Perinatology, 19(7), 488-493.Abstract
Objective: To identify predictors of symptomatic urinary tract infection (UTI) after 20 weeks' gestation.Study design: A retrospective cohort analysis was conducted of all deliveries at three North Carolina hospitals between 1990 and 1993. A total of 7403 deliveries remained after exclusions (pre-pregnancy diabetes, HIV-positive, structural urologic abnormalities, no prenatal care) and restrictions (black or white race, county of residence). Cystitis and pyelonephritis were identified by clinician diagnosis. Multiple logistic regression was conducted.
Results: Prior UTIs (both before and earlier in pregnancy), nonprivate clinics, and a history of chlamydia (white women only) doubled the risk of symptomatic UTIs after 20 weeks' gestation. The strongest predictor of pyelonephritis was prior antenatal UTIs (adjusted incidence odds ratio = 5.3, 95% confidence interval of 2.6-11.0), followed by less education (< 12 years), a history of chlamydia, nonprivate clinics, illicit drug use, sickle cell hemoglobinopathy, and being unmarried.
Conclusion: Medical history and demographic factors predict cystitis and pyelonephritis after 20 weeks' gestation. Prospective studies of pyelonephritis predictors and screening strategies are warranted.
URL
http://dx.doi.org/10.1038/sj.jp.7200264Reference Type
Journal ArticleYear Published
1999Journal Title
Journal of PerinatologyAuthor(s)
Pastore, Lisa M.Savitz, David A.
Thorp, John M., Jr.
Koch, Gary G.
Hertz-Picciotto, Irva
Irwin, Debra E.
ORCiD
Hertz-Picciotto - 000-0001-6952-2390Thorp - 0000-0002-9307-6690