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Kaufman, Jay S. & Flack, John M. (2005). Angiotensin-Converting Enzyme Inhibitors in Black Patients. Annals of Internal Medicine, 142(7), 589.


We read with interest the review by Brewster and colleagues (1) summarizing the effects of single antihypertensive agents on blood pressure and blood pressure control, as reported in clinical studies that enrolled black patients in both the Americas and Africa. The authors highlighted the observation that for angiotensin-converting enzyme (ACE) inhibitors, the summary effect on diastolic control (as a binary outcome) did not differ significantly from placebo. However, they also found that for these agents, changes in both systolic (


Reference Type

Journal Article

Year Published


Journal Title

Annals of Internal Medicine


Kaufman, Jay S.
Flack, John M.