CitationThorp, John M., Jr.; Mayer, David C.; & Kuller, Jeffrey A. (1999). Central Hemodynamic Effects of an Oxytocin Receptor Antagonist (Atosiban) in the Isolated, Perfused Rat Heart. Journal of the Society for Gynecologic Investigation, 6(4), 186-7.
AbstractObjective: Atosiban is a selective oxytocin receptor antagonist capable of inhibiting oxytocin-induced contractility of the uterus. Trials of this agent in intact animals and women as a tocolytic agent for preterm labor have shown atosiban to be devoid of cardiac effects. This is in contrast to other tocolytic agents, which have profound hemodynamic effects. We conducted this study to determine the cardiac effect of atosiban in the isolated, perfused rat heart model.
Reference TypeJournal Article
Journal TitleJournal of the Society for Gynecologic Investigation
Author(s)Thorp, John M., Jr.
Mayer, David C.
Kuller, Jeffrey A.