CitationTate, Deborah F.; Turner-McGrievy, Gabrielle; Lyons, Elizabeth; Stevens, June; Erickson, Karen; Polzien, Kristen; Diamond, Molly; Wang, Xiaoshan; & Popkin, Barry M. (2012). Replacing Caloric Beverages with Water or Diet Beverages for Weight Loss in Adults: Main Results of the Choose Healthy Options Consciously Everyday (CHOICE) Randomized Clinical Trial. American Journal of Clinical Nutrition, 95(3), 555-563. PMCID: PMC3632875
AbstractBACKGROUND: Replacement of caloric beverages with noncaloric beverages may be a simple strategy for promoting modest weight reduction; however, the effectiveness of this strategy is not known.
OBJECTIVE: We compared the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs).
DESIGN: Overweight and obese adults [n = 318; BMI (in kg/m(2)): 36.3 +/- 5.9; 84% female; age (mean +/- SD): 42 +/- 10.7 y; 54% black] substituted noncaloric beverages (water or DBs) for caloric beverages (>/=200 kcal/d) or made dietary changes of their choosing (AC) for 6 mo.
RESULTS: In an intent-to-treat analysis, a significant reduction in weight and waist circumference and an improvement in systolic blood pressure were observed from 0 to 6 mo. Mean (+/-SEM) weight losses at 6 mo were -2.5 +/- 0.45% in the DB group, -2.03 +/- 0.40% in the Water group, and -1.76 +/- 0.35% in the AC group; there were no significant differences between groups. The chance of achieving a 5% weight loss at 6 mo was greater in the DB group than in the AC group (OR: 2.29; 95% CI: 1.05, 5.01; P = 0.04). A significant reduction in fasting glucose at 6 mo (P = 0.019) and improved hydration at 3 (P = 0.0017) and 6 (P = 0.049) mo was observed in the Water group relative to the AC group. In a combined analysis, participants assigned to beverage replacement were 2 times as likely to have achieved a 5% weight loss (OR: 2.07; 95% CI: 1.02, 4.22; P = 0.04) than were the AC participants.
CONCLUSIONS: Replacement of caloric beverages with noncaloric beverages as a weight-loss strategy resulted in average weight losses of 2% to 2.5%. This strategy could have public health significance and is a simple, straightforward message. This trial was registered at clinicaltrials.gov as NCT01017783.
Reference TypeJournal Article
Journal TitleAmerican Journal of Clinical Nutrition
Author(s)Tate, Deborah F.
Popkin, Barry M.