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Citation

Ma, Kimberly K.; Mele, Lisa; Landon, Mark B.; Spong, Catherine Y.; Ramin, Susan M.; Casey, Brian M.; Wapner, Ronald J.; Varner, Michael W.; Rouse, Dwight J.; & Thorp, John M., Jr., et al. (2013). The Obstetric and Neonatal Implications of a Low Value on the 50-g Glucose Screening Test. American Journal of Perinatology, 30(9), 715-721. PMCID: PMC4022774

Abstract

Objective: To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes.
Study Design: This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL.
Results: Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results.
Conclusion: A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

URL

http://dx.doi.org/10.1055/s-0032-1331027

Reference Type

Journal Article

Year Published

2013

Journal Title

American Journal of Perinatology

Author(s)

Ma, Kimberly K.
Mele, Lisa
Landon, Mark B.
Spong, Catherine Y.
Ramin, Susan M.
Casey, Brian M.
Wapner, Ronald J.
Varner, Michael W.
Rouse, Dwight J.
Thorp, John M., Jr.
Sciscione, Anthony C.
Catalano, Patrick M.
Harper, Margaret A.
Saade, George R.
Caritis, Steve N.
Sorokin, Yoram
Peaceman, Alan M., for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network

PMCID

PMC4022774

ORCiD

Thorp - 0000-0002-9307-6690