Relationship of Early Pregnancy Waist-to-Hip Ratio versus Body Mass Index with Gestational Diabetes Mellitus and Insulin Resistance

Citation

Basraon, Sanmaan K.; Mele, Lisa; Myatt, Leslie; Roberts, James M.; Hauth, John C.; Leveno, Kenneth J.; Varner, Michael W.; Wapner, Ronald J.; Peaceman, Alan M.; & Ramin, Susan M., et al. (2016). Relationship of Early Pregnancy Waist-to-Hip Ratio versus Body Mass Index with Gestational Diabetes Mellitus and Insulin Resistance. American Journal of Perinatology, 33(1), 114-122. PMCID: PMC5283057

Abstract

Objective: To determine the risk of gestational diabetes mellitus (GDM) and insulin resistance (IR) in obesity defined by body mass index (BMI), waist-to-hip ratio (WHR), or both combined.
Methods: Secondary analysis of a randomized multicenter trial of antioxidant supplementation versus placebo in nulliparous low-risk women to prevent pregnancy associated hypertension. Women between 9 and 16 weeks with data for WHR and BMI were analyzed for GDM (n = 2,300). Those with fasting glucose and insulin between 22 and 26 weeks (n = 717) were analyzed for IR by homeostatic model assessment of IR (normal,

URL

http://dx.doi.org/10.1055/s-0035-1562928

Reference Type

Journal Article

Year Published

2016

Journal Title

American Journal of Perinatology

Author(s)

Basraon, Sanmaan K.
Mele, Lisa
Myatt, Leslie
Roberts, James M.
Hauth, John C.
Leveno, Kenneth J.
Varner, Michael W.
Wapner, Ronald J.
Peaceman, Alan M.
Ramin, Susan M.
Sciscione, Anthony C.
Tolosa, Jorge E.
Sorokin, Yoram, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network [John M. Thorp, Jr., Member]

PMCID

PMC5283057