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Examining the process of age change in cognitive function in relation to risk of Alzheimer's disease (AD) throughout the adult life span and how such process is different for men and women. In doing so, we will better understand how social disadvantages such as low socioeconomic status and social isolation get under the skin to influence biological pathways to cognitive health as individuals age. It contributes new knowledge that is critical for identifying the life stages in which intervention might be most effective, targeting AD prevention and treatment in men and women, and informing efforts to contain AD related healthcare costs in America.

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